pure garcinia cambogia (GC) is a small, pumpkin-shaped fruit that grows in Southeast Asia and India. The key active ingredient found in the rind of pure garcinia cambogia is hydroxycitric acid (HCA), which some research suggests can help certain people lose weight. (1)
Currently, there are at least 14 separate HCA-containing products sold over-the-counter to consumers labeled as “pure garcinia cambogia.” Most people are drawn to the idea of using GC because of the potential that it can provide near-effortless, quick weight loss without the need to change someone’s overall diet or lifestyle very much.
GC itself is not a new product; in fact, it’s been consumed in parts of Asia for many years, although not for the purpose of losing weight. Since GC (traditionally also known as the Malabar tamarind) first began to gain popularity in the U.S. several years ago — after appearing frequently in the media and on popular health-related TV shows — sales have gone up dramatically. More and more people are purchasing this so-called “weight loss miracle drug” in hopes of losing stubborn body and stomach fat they’ve been struggling with for years.
But just like most other weight-loss supplements, pills and products, studies regarding GC’s effects and safety have been mixed. While there’s some evidence that HCA might be able to aid in weight loss even when someone does not exercise often or change his or her diet very much, there’s also concerns regarding serious side effects that can occur, including liver damage or failure, anxiety, fatigue, dizziness, and digestive problems.
Remember that just because GC is derived from a natural fruit doesn’t mean it’s always completely safe. So is pure garcinia cambogia ultimately worth trying? What’s the truth with this purported weight-loss supplement? Let’s take a look at how HCA works, in what situations GC might be helpful, and what adverse reactions are possible when using any type of weight loss drug.
Finally, it’s worth considering the fact that time and time again we see various fad diets and products publicized to help boost weight loss — but what really works in the end is living a healthy lifestyle long term.
Does pure garcinia cambogia Work? What the Studies Tell Us
pure garcinia cambogia reviews, research results and weight loss testimonials have been mixed to say the least. By far the most well-publicized benefit of using pure garcinia cambogia is its ability to increase weight loss. Other claims that are commonly made about pure garcinia cambogia’s effects include:
loss of appetite or less of a desire to eat than usual
reduced cravings for unhealthy foods, such as sugar addiction
a more positive mood (including feeling happier, more energetic and less tired)
increased energy and concentration
stabilized blood sugar levels
improved bowel movements
reduced joint pains
improved cholesterol levels
stronger desire to be physically active
Most of the claims above have not been backed by scientific studies, however some have. Let’s review the benefits of pure garcinia cambogia that actually have some merit and seem to be effective in some manner.
1. Weight Loss
Some studies have found that pure garcinia cambogia might, in fact, be able to help with low amounts of fat loss, plus some of the other health concerns mentioned above, although its effectiveness is rarely strong or consistent. For example, research suggests that HCA works by blocking a certain enzyme called adenosine triphosphate-citrate-lyase, which contributes to the formation of fat cells. But studies comparing GC’s effects to controls have found that it might only increase weight loss by a mere one to two pounds on average.
These findings are exactly what researchers published in the Journal of Obesity in 2011. When they compared people who took pure garcinia cambogia extract to those who didn’t, the weight difference was very small (on average just about two pounds). Plus, it wasn’t even possible to conclude that GC was directly responsible for the additional pounds lost.
The meta-analysis reviewed results from 12 different trails involving GC and revealed a small, statistically significant difference in weight loss favoring use of pure garcinia cambogia products containing HCA slightly over use of a placebo. However, the analysis also found that some studies showed digestive side effects (“gastrointestinal adverse events”) were twice as common in HCA groups compared with placebo.
Results from various weight loss studies involving GC have been very mixed. One study in the meta-analysis reported a significant decrease in fat mass in the HCA group compared with placebo, two studies reported a significant decrease in visceral fat/subcutaneous fat/total fat areas in the HCA group compared with placebo, but two other studies found no significant difference at all between HCA and placebo. A study that was published in the Journal of the American Medical Association found that GC used for 12 weeks (1,500 milligrams dosage) “failed to produce significant weight loss and fat mass loss beyond that observed with placebo.” (2)
The conclusion of the meta-analysis regarding pure garcinia cambogia? Researchers summed up their findings by saying that “the magnitude of the effects are small, and the clinical relevance is uncertain. Future trials should be more rigorous and better reported.” (3) The bottom line is that if you’re struggling to lose weight, GC likely won’t be the answer, according to trial and controlled studies.
2. Lowering Appetite
Studies have also suggested that it’s possible that HCA found in pure garcinia cambogia can help lower someone’s appetite by increasing production of the neurotransmitter serotonin, which is associated with calm and happy feelings — and therefore, sometimes appetite suppression, less cravings and reduced desire for comfort foods. Animal studies show it might also help increase energy expenditure. (4)
Keep in mind, however, that this isn’t the case with all people, and there are other, potentially less risky ways to better manage your appetite and boost serotonin production (such as eating balanced meals with protein foods and healthy carbs at regular times throughout the day).
What is pure garcinia cambogia - Dr. Axe
3. Lower Cholesterol
There’s some support for pure garcinia cambogia being able to improve cholesterol levels and lower high triglycerides. It might also be able to help raise HDL “good” cholesterol. It’s not safe for anyone already taking medications that affect cholesterol, however, and its effects don’t seem to be very reliable or strong.
Studies have found that GC has “no significant effect on anthropometric parameters, REE, triglycerides or glucose levels” but might have a small effect on lowering cholesterol. (5) Keep in mind that there are also plenty of other natural ways to improve cholesterol levels, including exercising and eating more dietary fiber from high-fiber foods like veggies, nuts, seeds and beans.
4. Stabilized Blood Sugar
Finally, what about CG’s effects on blood sugar levels? Some evidence exists showing that pure garcinia cambogia can help control blood sugar by improving how cells take up glucose (sugar) to be used for energy. One way in which it might improve weight loss is through inhibition of pancreatic alpha amylase enzymes, changes in intestinal alpha glucosidase and alterations in fatty acid synthesis. This might be able to change how carbohydrates are metabolized. (6)
This might possibly help your body respond to insulin better, although it can raise the risk for having low blood sugar levels in some people, too. If you have a history of blood sugar swings, you’re prediabetic, diabetic or taking medications that alter insulin’s effects, GC might make your blood sugar drop dangerously low. While this doesn’t appear to happen in everyone who takes GC, it’s something else to consider and something to discuss with your doctor.
Potential pure garcinia cambogia Side Effects
While some people claim they don’t experience any side effects at all from using GC, others have had very different experiences. Here’s one disturbing account regarding the use of pure garcinia cambogia extract that you might not have heard about: It’s contributed to at least several patients winding up in the hospital with liver failure and needing emergency liver transplants.
A 2016 article published by the Transplantation Center at the Mayo Clinic reports that millions of Americans regularly use herbal supplements, often in pill form, but aren’t aware of their full effects. Many weight loss drugs pose potential hidden dangers and are “associated with hepatotoxicity and acute liver injury.” (7)
In the case of pure garcinia cambogia, it can easily be overused and is not very well-regulated. Some manufacturers recommend taking high doses multiple times per day, for example 30 to 60 minutes before every meal for eight to 12 weeks straight. (8) Aside from liver damage, other pure garcinia cambogia side effects that can occur include:
becoming fuzzy or weak
fatigue and brain fog
an increase in catching colds/lower immune function
dry mouth and bad breath
digestive issues like nausea, trouble eating or diarrhea
Something else to consider about GC is the long list of its potential medical/drug interactions. Many people should avoid pure garcinia cambogia due to how it can affect other medications, pregnancy, nutrient levels, blood sugar and more. pure garcinia cambogia can potentially interact badly with: (9)
pregnancy and breastfeeding
existing cases of liver or kidney damage
medications that are taken to control asthma and allergies
diabetes medications and insulin
iron supplements (usually taken by people with anemia)
medications used to control mental disorders like anxiety and depression
statin drugs that lower cholesterol
blood thinning drugs (like warfarin)
How Much pure garcinia cambogia Should You Take?
If you decide that you still want to try taking GC for weight loss or its other benefits, here’s what you need to know about dosage recommendations for products containing HCA:
Studies using GC have used a wide range of doses, anywhere from one gram to 2.8 grams daily. Typical doses are ususally between 250–1,000 milligrams per day.
Study durations have also varied widely, ranging from using GC between two to 12 weeks at a time.
The optimal dose of HCA is currently still unknown. It’s not clear if a higher HCA dosage even means a higher bioavailability of HCA once consumed.
There does seem to be a significant correlation between the dosage of HCA and body weight loss, meaning higher doses have slightly more effects.
pure garcinia cambogia continues to be the most widely used supplement in studies for providing HCA, however aside from GC, HCA can also be found in supplements made from the plant Hibiscus subdariffa.
Because most studies have investigated the effects of GC taken for about eight weeks, researchers believe this is ultimately “too short a time to assess the effects of HCA on body weight.”
To err on the safe side, avoid buying pure garcinia cambogia “formulas” or “supplement blends,” which might fail to report all of the other ingredients included or accurate levels of HCA. Many proprietary formulas are made by manufacturers that only use a fraction of the active ingredient or standard dose to keep costs down. Always read labels and look for the words “pure pure garcinia cambogia” and “hydroxycitric acid (or HCA) extract” (this should be around 50 percent to 60 percent of the product). If you purchase a blend and see an ingredient listed without an amount, that can be a red flag that you don’t know exactly what you’re getting.
pure garcinia cambogia side effects - Dr. Axe
11 Weight Loss Methods That Really Do Work
In just about all studies involving pure garcinia cambogia, researchers note that it’s hard to tell if any demonstrated benefits (weight loss, reduced cholesterol, etc.) are really due to GC or are actually influenced by other factors like the subjects eating lower-calorie diets or exercising. It’s always possible for any supplement to cause a “placebo effect,” where subjects wind up changing their outlook and habits simply because they believe the product is helping them (even if it isn’t actually doing anything).
Another interesting fact that the Journal of Obesity meta-analsis reports is that most of the included studies “failed to indicate whether or not outcome assessors were blinded, and seven studies did not even specify who funded the pure garcinia cambogia studies.” While it’s possible that pure garcinia cambogia might help you lose an additional one to two pounds if you take it regularly, most experts don’t think it’s worth the money or the risk — especially considering its effects are so small and inconsistent.
Ultimately, taking weight loss supplements won’t teach you much about eating an overall healthy diet, finding ways to enjoy exercise, or practicing “intuitive eating” and managing cravings. So what can you do to move in the right direction of losing weight safely? Weight loss efforts should always be realistic, safe and sustainable. Remember that the real goal is to reach a healthy weight and stay there for life. That’s why quick fixes and fad diets have been shown in studies to fail in the long run over 95 percent of the time.
Here are some of my favorite tips for losing weight using reliable methods that really work:
Get good sleep! A lack of sleep (less than seven to nine hours nightly for most people) can mean a lack of weight loss.
Eat more fiber: Adults need to aim for at least 25–30 grams daily from things like veggies, fruit, ancient grains, sprouted legumes and seeds.
Use healthy fats: Coconut oil has natural fat-burning effects just like GC does, plus many more benefits like improving gut health, too. Other healthy fats that can help control your appetite include real olive oil, avocado, fats from grass-fed beef, nuts and seeds.
Utilize adaptogen herbs: Adaptogen herbs like maca, ginseng and rhodiola can help control health conditions that can make it hard to lose weight (like high amounts of stress, thyroid issues, leaky gut, adrenal fatigue, cellular toxicity and candida).
Don’t skimp on protein: Protein foods are satisfying and essential for building muscles. Regularly include proteins like cage-free eggs and wild-caught fish in your meals.
Consume probiotics: Probiotic foods and supplements not only help balance improve digestive health, but they also balance hormones, raise immunity, control your appetite and play a part in weight control.
Switch up your exercise routine: Try burst-training exercises and other forms of high intensity interval training (HIIT) to keep challenging your muscles, work in with a group, add in weight training, and relax with yoga in between workouts.
Stand up more during the day: Sitting for long periods of time is associated with being overweight and a higher risk for obesity.
Sneak more fitness into your day: Take the stairs, do body weight exercises at home. or try wearing a fitness tracker for motivation — try some of these exercise hacks.
Schedule your workouts ahead of time: This makes it much more likely you’ll follow through.
Use essential oils for weight loss: Natural oils including grapefruit, cinnamon and ginger oil can help control your appetite, hormones and digestive symptoms.
Read Next: Basal Metabolic Rate — What “The Biggest Loser” Can Teach Us
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